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Gastrointestinal diagnostics

Overview of laboratory services

More than 30% of the population suffers from indistinct abdominal symptoms characterised by flatulence, recurrent diarrhoea, constipation, abdominal cramps or vomiting. These symptoms could be caused by a lack of digestive enzymes or bile acids (maldigestion), a disturbance of enteral food absorption (malabsorption) or an extremely high-fat and protein-rich diet (malnutrition). More than 70 million diseases of the gastrointestinal tract are registered in Germany every year. Causes include infections, an unhealthy diet, the intake of medication, psychological stress, dental toxins and other toxins. A broad spectrum of laboratory diagnostic analyses can be used to clarify gastrointestinal complaints, from the detection of an impaired intestinal microflora to the detection of impaired intestinal permeability.

Intestinal microbiota

The intestinal microbiota consists of about 1,000 different types of bacteria. They are essential for digestion, vitamin synthesis and amino acids, and for strengthening the immune system. Every human being has an individual composition of intestinal…

Examination of the intestinal microflora

The Stool Flora Analysis can be used to detect changes in the mucosa and disorders of the microflora. This microbiological examination is suitable for monitoring the progression of gastrointestinal and multi-causal diseases. In adults, the unfolding…

Malabsorption

Alpha-1-antitrypsin (AAT) can be used as a marker for increased intestinal permeability of the intestinal mucosa (Leaky Gut Syndrome). AAT is a 52 Kd glycoprotein produced in the liver and by intestinal macrophages, monocytes and intestinal…

Maldigestion

The concentration of pancreatic elastase in the stool allows conclusions about the exocrine pancreatic function. Non-specific symptoms, such as changing stools, upper abdominal discomfort, nausea, colic-like pain, feeling of fullness, meteorism, food…

Inflammatory bowel diseases

The eosinophilic protein X (EPX) is released by activated eosinophilic granulocytes and plays an important role as a cytotoxic protein in the defence against parasites and bacteria. Increased release can be triggered by IgE-mediated food allergies,…

Intestinal permeability

If intestinal colonisation is abnormal, the intestinal flora is only able to fulfil its physiological tasks to a limited extent. The resulting disorder of the microbial barrier ultimately results in pathomechanisms that lead to latent inflammatory…

Firmicutes-Bacteroidetes ratio

Numerous studies conducted in recent years have shown a connection between body weight and individual intestinal flora. These showed: The lower the proportion of the Firmicutes bacterial strains (or the higher the proportion of Bacteroidetes), the…

Bacterial metabolic activity

Butter, propionic and acetic acid ensure a stable barrier function of the intestine. The short-chain fatty acids butyric, propionic and acetic acid are formed during the microbial metabolism of fibre from cereals or the cell walls of vegetables in…